The Journal of Informed Pharmacotherapy

     

Copyright
(c) 2002 JIP


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Form for Evaluating an Article on the Clinical Impact of Drug Therapy

Reviewer:

Reviewer's email address:

Reviewer's profession/specialty:

Citation:
_______________________________________________ _______________________________________________ _______________________________________________

After each main question, other questions have been added in smaller font to help guide your answers.

Overall Study Question:

What were the objectives, the patient population, the outcome variables, and the interventions tested in this trial?

 

 

 

 

 

 

Are the Results of the Study Valid?

          1. Was assignment of randomized?

[ ] Yes
[ ] No
[ ] Can't Tell

 

 

           2. Were all patients who entered the trial properly  
           accounted for and attributed at its conclusion?- was 
              follow-up  complete? - were patients analyzed in the groups to which they
              were randomized (intention to treat analysis)?
[ ] Yes
[ ] No
[ ] Can't Tell
 
 
 
 
 
3. Were patients, their clinicians, and study personnel 'blind' to treatment?
[ ] Yes
[ ] No
[ ] Can't Tell

 

 

4. Were the groups similar at the start of the trial? Baseline prognostic factors (demographics, co-morditity, disease severity, other known confounders) balanced? - If different, were these adjusted for?
 
[ ] Yes
[ ] No
[ ] Can't Tell
 
 
 
 
 
 
 
 
5. Aside from the experimental intervention, were the groups treated equally? Co-intervention? Contamination?
Compliance?
[ ] Yes
[ ] No
[ ] Can't Tell
 
 
 
 
 
 
 
 
 
6. Overall, are the results of the study valid?
[ ] Yes
[ ] No
[ ] Can't Tell

 

 

 

 

 



What are the Results

1. How large was the treatment effect?  Absolute risk reduction? Relative risk reduction?   

 

 

 

 

 

          2. How precise was the estimate of the treatment effect?    Confidence intervals?  

  

 


 

 


Will the Results Help Me in Caring for My Patients?

1. Can the results be applied to my patient care? Patients similar for demographics, severity, co-morbidity and other prognostic factors? Compelling reason why the results should not be applied?
[ ] Yes
[ ] No
[ ] Can't Tell

 

 
 
          2. Were all clinically important outcomes considered?
          Are  substitute endpoints valid?
[ ] Yes
[ ] No
[ ] Can't Tell

 

 

 

3. Are the likely treatment benefits worth the potential harms and costs? NNT for different outcomes?  
[ ] Yes
[ ] No
[ ] Can't Tell

 

 


        Commentary

  • (to provide the contexts of previous knowledge and clinical practice within which the results of the abstracted study apply, any important methodological problems that affect interpretation of the study results, and recommendations for the  application of the study findings to the field of clinical pharmacotherapy)

Please direct any inquiries or comments about the Journal to the Managing/ Founding  Editors.  If you have any recommendations for journal content, we would be pleased to receive your ideas.

Last updated: March 27, 2000